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Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase

The outbreak of SARS, a life-threatening disease, has spread over many countries around the world. So far there is no effective drug for the treatment of SARS. Stimulated by the binding mechanism of SARS-CoV M(pro) with the octapeptide AVLQSGFR reported recently as well as the “Chou's distorted...

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Detalhes bibliográficos
Publicado no:Peptides
Main Authors: Gan, Yi-Ru, Huang, He, Huang, Yong-Dong, Rao, Chun-Ming, Zhao, Yang, Liu, Jin-Sheng, Wu, Lei, Wei, Dong-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115688/
https://ncbi.nlm.nih.gov/pubmed/16242214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2005.09.006
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