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The substrate specificity of SARS coronavirus 3C-like proteinase
The 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS) has been proposed to be a key target for structural based drug design against SARS. We have designed and synthesized 34 peptide substrates and determined their hydrolysis activities. The conserved core sequence of the nat...
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| Publicat a: | Biochem Biophys Res Commun |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Inc.
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7092912/ https://ncbi.nlm.nih.gov/pubmed/15752746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.02.061 |
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