Loss of expression of both miR-15/16 loci in CML transition to blast crisis

Despite advances that have improved the treatment of chronic myeloid leukemia (CML) patients in chronic phase, the mechanisms of the transition from chronic phase CML to blast crisis (BC) are not fully understood. Considering the key role of miR-15/16 loci in the pathogenesis of myeloid and lymphocy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lovat, Francesca, Gasparini, Pierluigi, Nigita, Giovanni, Larkin, Karilyn, Byrd, John C., Minden, Mark D., Andreeff, Michael, Carter, Bing Z., Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980455/
https://ncbi.nlm.nih.gov/pubmed/33836616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2101566118
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