PRMT6 Methylation of RCC1 Regulates Mitosis, Tumorigenicity, and Radiation Response of Glioblastoma Stem Cells

Aberrant cell proliferation is a hallmark of cancer including glioblastoma (GBM). Here we report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, stem-like properties, and tumorigenicity of glioblastoma stem cells (GSCs), a subpopulation in GBM critical fo...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Huang, Tianzhi, Yang, Yongyong, Song, Xiao, Wan, Xuechao, Wu, Bingli, Sastry, Namratha, Horbinski, Craig M., Zeng, Chang, Tiek, Deanna, Goenka, Anshika, Liu, Fabao, Brennan, Cameron W., Kessler, John A., Stupp, Roger, Nakano, Ichiro, Sulman, Erik P., Nishikawa, Ryo, James, Charles David, Zhang, Wei, Xu, Wei, Hu, Bo, Cheng, Shi-Yuan
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979509/
https://ncbi.nlm.nih.gov/pubmed/33539787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.01.015
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