CSIG-35. MST4 PHOSPHORYLATION OF ATG4B REGULATES AUTOPHAGIC ACTIVITY, TUMORIGENICITY, AND RADIORESISTANCE IN GLIOBLASTOMA

Autophagy is a conserved catabolic process that maintains homeostasis by regulating the energy balance of the cell. Cancer cells use autophagy to remove damaged organelles and aggregated proteins, and to recycle nutrients in high demand to support tumor growth. Radiation therapy (RT) and temozolomid...

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Publicado no:Neuro Oncol
Main Authors: Huang, Tianzhi, Kwon Kim, Chung, Alvarez, Angel, Pangeni, Rajendra, Wan, Xuechao, Xiao, Song, Shi, Taiping, Yang, Yongyong, Sastry, Namratha, Horbinski, Craig, Lu, Songjian, Stupp, Roger, Kessler, John, Nishikawa, Ryo, Nakano, Ichiro, Sulman, Erik, Lu, Xinghua, James, C David, Yin, Xiao-Ming, Hu, Bo, Cheng, Shi-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216764/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.201
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