Integrating Genome and Functional Genomics Data to Reveal Perturbed Signaling Pathways in Ovarian Cancers

Por Lu, Songjian, Lu, Xinghua
Publicado em 2012

Using graph models to find transcription factor modules: the hitting set problem and an exact algorithm

Por Lu, Songjian, Lu, Xinghua
Publicado em 2013

An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem

Por Lu, Songjian, Mandava, Gunasheil, Yan, Gaibo, Lu, Xinghua
Publicado no Algorithms Mol Biol (2016)

A signal-based method for finding driver modules of breast cancer metastasis to the lung

Por Yan, Gaibo, Chen, Vicky, Lu, Xinghua, Lu, Songjian
Publicado no Sci Rep (2017)

From Data towards Knowledge: Revealing the Architecture of Signaling Systems by Unifying Knowledge Mining and Data Mining of Systematic Perturbation Data

Por Lu, Songjian, Jin, Bo, Cowart, L. Ashley, Lu, Xinghua
Publicado em 2013

Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets

Por Lu, Songjian, Lu, Kevin N., Cheng, Shi-Yuan, Hu, Bo, Ma, Xiaojun, Nystrom, Nicholas, Lu, Xinghua
Publicado no PLoS Comput Biol (2015)

Distinct Signaling Roles of Ceramide Species in Yeast Revealed Through Systematic Perturbation and Systems Biology Analyses

Por Montefusco, David J., Chen, Lujia, Matmati, Nabil, Lu, Songjian, Newcomb, Benjamin, Cooper, Gregory F., Hannun, Yusuf A., Lu, Xinghua
Publicado em 2013

Signal-oriented pathway analyses reveal a signaling complex as a synthetic lethal target for p53 mutations

Por Lu, Songjian, Cai, Chunhui, Yan, Gonghong, Zhou, Zhuan, Wan, Yong, Chen, Vicky, Chen, Lujia, Cooper, Gregory F., Obeid, Lina M., Hannun, Yusuf A., Lee, Adrian V., Lu, Xinghua
Publicado no Cancer Res (2016)

Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

Por Feng, Haizhong, Hu, Bo, Liu, Kun-Wei, Li, Yanxin, Lu, Xinghua, Cheng, Tao, Yiin, Jia-Jean, Lu, Songjian, Keezer, Susan, Fenton, Tim, Furnari, Frank B., Hamilton, Ronald L., Vuori, Kristiina, Sarkaria, Jann N., Nagane, Motoo, Nishikawa, Ryo, Cavenee, Webster K., Cheng, Shi-Yuan
Publicado em 2011

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways

Por Huang, Tianzhi, Alvarez, Angel A., Pangeni, Rajendra P., M. Horbinski, Craig, Lu, Songjian, Kim, Sung-Hak, James, C. David, J. Raizer, Jeffery, A. Kessler, John, Brenann, Cameron W., Sulman, Erik P., Finocchiaro, Gaetano, Tan, Ming, Nishikawa, Ryo, Lu, Xinghua, Nakano, Ichiro, Hu, Bo, Cheng, Shi-Yuan
Publicado no Nat Commun (2016)

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

Por Huang, Tianzhi, Kim, Chung Kwon, Alvarez, Angel A., Pangeni, Rajendra P., Wan, Xuechao, Song, Xiao, Shi, Taiping, Yang, Yongyong, Sastry, Namratha, Horbinski, Craig M., Lu, Songjian, Stupp, Roger, Kessler, John A., Nishikawa, Ryo, Nakano, Ichiro, Sulman, Erik P., Lu, Xinghua, James, Charles David, Yin, Xiao-Ming, Hu, Bo, Cheng, Shi-Yuan
Publicado no Cancer Cell (2017)

Activation of the receptor tyrosine kinase AXL regulates the immune microenvironment in glioblastoma

Por Sadahiro, Hirokazu, Kang, Kyung-Don, Gibson, Justin T., Minata, Mutsuko, Yu, Hai, Shi, Junfeng, Chhipa, Rishi, Chen, Zhihong, Lu, Songjian, Simoni, Yannick, Furuta, Takuya, Sabit, Hemragul, Zhang, Suojun, Bastola, Soniya, Yamaguchi, Shinobu, Alsheikh, Hebaallah, Komarova, Svetlana, Wang, Jun, Kim, Sung-Hak, Hambardzumyan, Dolores, Lu, Xinghua, Newell, Evan W., DasGupta, Biplab, Nakada, Mitsutoshi, Lee, L. James, Nabors, Burt, Norian, Lyse A., Nakano, Ichiro
Publicado no Cancer Res (2018)