SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes

Mis-regulated alternative RNA splicing (AS) contributes to the tumorigenesis and progression of human cancers, including glioblastoma (GBM). Here, we showed that a major splicing factor, serine and arginine rich splicing factor 3 (SRSF3) was frequently upregulated in clinical glioma specimens and th...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Song, Xiao, Wan, Xuechao, Huang, Tianzhi, Zeng, Chang, Sastry, Namratha, Wu, Bingli, James, C. David, Horbinski, Craig, Nakano, Ichiro, Zhang, Wei, Hu, Bo, Cheng, Shi-Yuan
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801100/
https://ncbi.nlm.nih.gov/pubmed/31462429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1504
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