PRMT6 Methylation of RCC1 Regulates Mitosis, Tumorigenicity, and Radiation Response of Glioblastoma Stem Cells

Aberrant cell proliferation is a hallmark of cancer including glioblastoma (GBM). Here we report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, stem-like properties, and tumorigenicity of glioblastoma stem cells (GSCs), a subpopulation in GBM critical fo...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Huang, Tianzhi, Yang, Yongyong, Song, Xiao, Wan, Xuechao, Wu, Bingli, Sastry, Namratha, Horbinski, Craig M., Zeng, Chang, Tiek, Deanna, Goenka, Anshika, Liu, Fabao, Brennan, Cameron W., Kessler, John A., Stupp, Roger, Nakano, Ichiro, Sulman, Erik P., Nishikawa, Ryo, James, Charles David, Zhang, Wei, Xu, Wei, Hu, Bo, Cheng, Shi-Yuan
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979509/
https://ncbi.nlm.nih.gov/pubmed/33539787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.01.015
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires