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PRMT6 Methylation of RCC1 Regulates Mitosis, Tumorigenicity, and Radiation Response of Glioblastoma Stem Cells
Aberrant cell proliferation is a hallmark of cancer including glioblastoma (GBM). Here we report that protein arginine methyltransferase (PRMT) 6 activity is required for the proliferation, stem-like properties, and tumorigenicity of glioblastoma stem cells (GSCs), a subpopulation in GBM critical fo...
Shranjeno v:
| izdano v: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979509/ https://ncbi.nlm.nih.gov/pubmed/33539787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.01.015 |
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