LY6K promotes glioblastoma tumorigenicity via CAV-1–mediated ERK1/2 signaling enhancement

BACKGROUND: Lymphocyte antigen 6 complex, locus K (LY6K) is a putative oncogene in various cancers. Elevated expression of LY6K is correlated with poor patient prognosis in glioblastoma (GBM). The aim of this study is to advance our understanding of the mechanism by which LY6K contributes to GBM tum...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Sastry, Namratha G, Wan, Xuechao, Huang, Tianzhi, Alvarez, Angel A, Pangeni, Rajendra P, Song, Xiao, James, Charles David, Horbinski, Craig M, Brennan, Cameron W, Nakano, Ichiro, Hu, Bo, Cheng, Shi-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523463/
https://ncbi.nlm.nih.gov/pubmed/32055849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa032
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