LY6K promotes glioblastoma tumorigenicity via CAV-1–mediated ERK1/2 signaling enhancement

BACKGROUND: Lymphocyte antigen 6 complex, locus K (LY6K) is a putative oncogene in various cancers. Elevated expression of LY6K is correlated with poor patient prognosis in glioblastoma (GBM). The aim of this study is to advance our understanding of the mechanism by which LY6K contributes to GBM tum...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sastry, Namratha G, Wan, Xuechao, Huang, Tianzhi, Alvarez, Angel A, Pangeni, Rajendra P, Song, Xiao, James, Charles David, Horbinski, Craig M, Brennan, Cameron W, Nakano, Ichiro, Hu, Bo, Cheng, Shi-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523463/
https://ncbi.nlm.nih.gov/pubmed/32055849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa032
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