The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

Cells and organisms have a wide range of mechanisms to defend against infection by viruses and other mobile genetic elements (MGE). Type III CRISPR systems detect foreign RNA and typically generate cyclic oligoadenylate (cOA) second messengers that bind to ancillary proteins with CARF (CRISPR associ...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Zhu, Wenlong, McQuarrie, Stuart, Grüschow, Sabine, McMahon, Stephen A, Graham, Shirley, Gloster, Tracey M, White, Malcolm F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2021
Aiheet:
Nucleic Acid Enzymes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969007/
https://ncbi.nlm.nih.gov/pubmed/33590098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab073
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