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Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
The CRISPR system provides adaptive immunity against mobile genetic elements (MGE) in prokaryotes. In type III CRISPR systems, an effector complex programmed by CRISPR RNA detects invading RNA, triggering a multi-layered defence that includes target RNA cleavage, licencing of an HD DNA nuclease doma...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755085/ https://ncbi.nlm.nih.gov/pubmed/31392987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz676 |
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