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Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence

The CRISPR system provides adaptive immunity against mobile genetic elements (MGE) in prokaryotes. In type III CRISPR systems, an effector complex programmed by CRISPR RNA detects invading RNA, triggering a multi-layered defence that includes target RNA cleavage, licencing of an HD DNA nuclease doma...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Grüschow, Sabine, Athukoralage, Januka S, Graham, Shirley, Hoogeboom, Tess, White, Malcolm F
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755085/
https://ncbi.nlm.nih.gov/pubmed/31392987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz676
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