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Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence
Type III CRISPR systems synthesise cyclic oligoadenylate (cOA) second messengers in response to viral infection of bacteria and archaea, potentiating an immune response by binding and activating ancillary effector nucleases such as Csx1. As these effectors are not specific for invading nucleic acids...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293037/ https://ncbi.nlm.nih.gov/pubmed/32347937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa298 |
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