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Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
The CRISPR system provides adaptive immunity against mobile genetic elements (MGE) in prokaryotes. In type III CRISPR systems, an effector complex programmed by CRISPR RNA detects invading RNA, triggering a multi-layered defence that includes target RNA cleavage, licencing of an HD DNA nuclease doma...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755085/ https://ncbi.nlm.nih.gov/pubmed/31392987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz676 |
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