Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

Optogenetic control of CRISPR–Cas9 systems has significantly improved our ability to perform genome perturbations in living cells with high precision in time and space. As new Cas orthologues with advantageous properties are rapidly being discovered and engineered, the need for straightforward strat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Hoffmann, Mareike D, Mathony, Jan, Upmeier zu Belzen, Julius, Harteveld, Zander, Aschenbrenner, Sabine, Stengl, Christina, Grimm, Dirk, Correia, Bruno E, Eils, Roland, Niopek, Dominik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Methods Online
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969004/
https://ncbi.nlm.nih.gov/pubmed/33330940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1198
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