USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

DNA–protein cross-links (DPCs) are toxic DNA lesions that interfere with DNA metabolic processes such as replication, transcription, and recombination. USP11 deubiquitinase participates in DNA repair, but the role of USP11 in DPC repair is not known. SPRTN is a replication-coupled DNA-dependent meta...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Perry, Megan, Biegert, Meghan, Kollala, Sai Sundeep, Mallard, Halle, Su, Grace, Kodavati, Manohar, Kreiling, Natasha, Holbrook, Alexander, Ghosal, Gargi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960550/
https://ncbi.nlm.nih.gov/pubmed/33567341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100396
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