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Deubiquitination and activation of AMPK by USP10
The AMP-activated protein kinase (AMPK) is the master regulator of metabolic homeostasis by sensing cellular energy status. When intracellular ATP levels decrease during energy stress, AMPK is initially activated through AMP or ADP binding and phosphorylation of a threonine residue (Thr-172) within...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836875/ https://ncbi.nlm.nih.gov/pubmed/26876938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.010 |
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