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Deubiquitination and activation of AMPK by USP10

The AMP-activated protein kinase (AMPK) is the master regulator of metabolic homeostasis by sensing cellular energy status. When intracellular ATP levels decrease during energy stress, AMPK is initially activated through AMP or ADP binding and phosphorylation of a threonine residue (Thr-172) within...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Deng, Min, Yang, Xu, Qin, Bo, Liu, Tongzheng, Zhang, Haoxing, Guo, Wei, Lee, Seung Baek, Kim, Jung Jin, Yuan, Jian, Pei, Huadong, Wang, Liewei, Lou, Zhenkun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836875/
https://ncbi.nlm.nih.gov/pubmed/26876938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.010
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