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DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability

DBC1 (deleted in breast cancer 1), also known as CCAR2 or KIAA1967 is an important negative regulator of SIRT1 and cellular stress response. Although the Dbc1 gene localizes at a region that is homozygously deleted in breast cancer, its role in tumorigenesis remains unclear. It has been suggested to...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Qin, Bo, Minter-Dykhouse, Katherine, Yu, Jia, Zhang, Jun, Liu, Tongzheng, Zhang, Haoxing, Lee, Seung Baek, Kim, Jung Jin, Wang, Liewei, Lou, Zhenkun
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351187/
https://ncbi.nlm.nih.gov/pubmed/25732823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.066
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