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DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability
DBC1 (deleted in breast cancer 1), also known as CCAR2 or KIAA1967 is an important negative regulator of SIRT1 and cellular stress response. Although the Dbc1 gene localizes at a region that is homozygously deleted in breast cancer, its role in tumorigenesis remains unclear. It has been suggested to...
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| Publié dans: | Cell Rep |
|---|---|
| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351187/ https://ncbi.nlm.nih.gov/pubmed/25732823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.066 |
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