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Deubiquitination and activation of AMPK by USP10
The AMP-activated protein kinase (AMPK) is the master regulator of metabolic homeostasis by sensing cellular energy status. When intracellular ATP levels decrease during energy stress, AMPK is initially activated through AMP or ADP binding and phosphorylation of a threonine residue (Thr-172) within...
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| 發表在: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836875/ https://ncbi.nlm.nih.gov/pubmed/26876938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.010 |
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