Deubiquitination and activation of AMPK by USP10

The AMP-activated protein kinase (AMPK) is the master regulator of metabolic homeostasis by sensing cellular energy status. When intracellular ATP levels decrease during energy stress, AMPK is initially activated through AMP or ADP binding and phosphorylation of a threonine residue (Thr-172) within...

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Publicado en:Mol Cell
Autores principales: Deng, Min, Yang, Xu, Qin, Bo, Liu, Tongzheng, Zhang, Haoxing, Guo, Wei, Lee, Seung Baek, Kim, Jung Jin, Yuan, Jian, Pei, Huadong, Wang, Liewei, Lou, Zhenkun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836875/
https://ncbi.nlm.nih.gov/pubmed/26876938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.010
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