Deubiquitination and stabilization of PTEN by USP13

The tumor suppressor PTEN is frequently lost in human cancers. In addition to gene mutations and deletions, recent studies have revealed the importance of post-translational modifications, such as ubiquitination, in the regulation of PTEN stability, activity and localization. However, the deubiquiti...

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Hlavní autoři: Zhang, Jinsong, Zhang, Peijing, Wei, Yongkun, Piao, Hai-long, Wang, Wenqi, Maddika, Subbareddy, Wang, Min, Chen, Dahu, Sun, Yutong, Hung, Mien-Chie, Chen, Junjie, Ma, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951854/
https://ncbi.nlm.nih.gov/pubmed/24270891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2874
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