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Deubiquitination and stabilization of PTEN by USP13
The tumor suppressor PTEN is frequently lost in human cancers. In addition to gene mutations and deletions, recent studies have revealed the importance of post-translational modifications, such as ubiquitination, in the regulation of PTEN stability, activity and localization. However, the deubiquiti...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951854/ https://ncbi.nlm.nih.gov/pubmed/24270891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2874 |
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