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Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13
Autophagy is an important intracellular catabolic mechanism that mediates the degradation of cytoplasmic proteins and organelles. We report a potent small molecule inhibitor of autophagy named “spautin-1” for specific and potent autophagy inhibitor-1. Spautin-1 promotes the degradation of Vps34 PI3...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441147/ https://ncbi.nlm.nih.gov/pubmed/21962518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.037 |
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