USP9X-triggered ferroptosis mediates follicular atresia via deubiquitinating Beclin1 in chicken

Abstract Background Follicular atresia, a complex degenerative process regulated by multiple molecular mechanisms, significantly affects female reproductive performance in animals. While granulosa cell (GC) apoptosis has been well established as a primary mechanism underlying follicular atresia, the...

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Hlavní autoři:	Yuqi Chen, Wenjuan Wang, Can Cui, Yao Zhang, Zhuanjian Li, Huadong Yin, Shunshun Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-10-01
Edice:	Journal of Animal Science and Biotechnology
Témata:	Autophagy Beclin1 Ferroptosis Follicular atresia Ubiquitination USP9X
On-line přístup:	https://doi.org/10.1186/s40104-025-01269-8
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