MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria

Mutations in mitochondrial replicative polymerase PolγA lead to progressive external ophthalmoplegia (PEO). While PolγA is the known central player in mitochondrial DNA (mtDNA) replication, it is unknown whether a regulatory process exists on the mitochondrial outer membrane which controlled its ent...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Hussain, Mansoor, Mohammed, Aftab, Saifi, Shabnam, Khan, Aamir, Kaur, Ekjot, Priya, Swati, Agarwal, Himanshi, Sengupta, Sagar
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959396/
https://ncbi.nlm.nih.gov/pubmed/33657094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001139
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker