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Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes

Ubiquitylation of outer mitochondrial membrane (OMM) proteins is closely related to the onset of familial Parkinson's disease. Typically, a reduction in the mitochondrial membrane potential results in Parkin‐mediated ubiquitylation of OMM proteins, which are then targeted for proteasomal and mi...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Koyano, Fumika, Yamano, Koji, Kosako, Hidetaka, Kimura, Yoko, Kimura, Mayumi, Fujiki, Yukio, Tanaka, Keiji, Matsuda, Noriyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893362/
https://ncbi.nlm.nih.gov/pubmed/31602805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947728
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