Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis

[Image: see text] There is a critical unmet need for therapeutics to treat the epidemic of comorbidities associated with obesity and type 2 diabetes, ideally devoid of nausea/emesis. This study developed monomeric peptide agonists of glucagon-like peptide 1 receptor (GLP-1R) and neuropeptide Y2 rece...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Med Chem
Main Authors: Milliken, Brandon T., Elfers, Clinton, Chepurny, Oleg G., Chichura, Kylie S., Sweet, Ian R., Borner, Tito, Hayes, Matthew R., De Jonghe, Bart C., Holz, George G., Roth, Christian L., Doyle, Robert P.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956155/
https://ncbi.nlm.nih.gov/pubmed/33449689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01783
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker