GDF15 Induces Anorexia through Nausea and Emesis

Growth differentiation factor 15 (GDF15) is a cytokine that reduces food intake through activation of hindbrain GFRAL-RET receptors and has become a keen target of interest for anti-obesity therapies. Elevated endogenous GDF15 is associated with energy balance disturbances, cancer progression, chemo...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Borner, Tito, Shaulson, Evan D., Ghidewon, Misgana Y., Barnett, Amanda B., Horn, Charles C., Doyle, Robert P., Grill, Harvey J., Hayes, Matthew R., De Jonghe, Bart C.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161938/
https://ncbi.nlm.nih.gov/pubmed/31928886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.12.004
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