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p53 and tumor suppression: it takes a network
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumorigenesis by transcriptionally regulating a network of target genes that play roles in various cellular processes. Though originally characterized as a critical regulator for responses to acute DNA dama...
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| Pubblicato in: | Trends Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954925/ https://ncbi.nlm.nih.gov/pubmed/33518400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2020.12.011 |
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