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Deconstructing networks of p53-mediated tumor suppression in vivo
The transcription factor p53 is a vital tumor suppressor. Upon activation by diverse stresses including oncogene activation, DNA damage, hypoxia and nutrient deprivation, p53 activates a panoply of target genes and orchestrates numerous downstream responses that suppress tumorigenesis. Although earl...
Shranjeno v:
| izdano v: | Cell Death Differ |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5729531/ https://ncbi.nlm.nih.gov/pubmed/29099489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.171 |
| Oznake: |
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