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p53 and tumor suppression: it takes a network
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumorigenesis by transcriptionally regulating a network of target genes that play roles in various cellular processes. Though originally characterized as a critical regulator for responses to acute DNA dama...
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| Vydáno v: | Trends Cell Biol |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954925/ https://ncbi.nlm.nih.gov/pubmed/33518400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2020.12.011 |
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