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Tumor Suppression: p53 Alters Immune Surveillance to Restrain Liver Cancer
The p53 tumor suppressor governs multiple cell-intrinsic programs, including cell-cycle arrest and apoptosis, to curb neoplastic growth. A new study reveals that p53 also acts through a novel non-cell-autonomous mechanism, by stimulating the innate immune system to maintain tissue homeostasis and su...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077325/ https://ncbi.nlm.nih.gov/pubmed/23787049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.04.076 |
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