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Deconstructing p53 transcriptional networks in tumor suppression
p53 is a pivotal tumor suppressor which induces apoptosis, cell-cycle arrest and senescence in response to stress signals. Although p53 transcriptional activation is important for these responses, the mechanisms underlying tumor suppression have been elusive. To date, no single or compound mouse kno...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3541866/ https://ncbi.nlm.nih.gov/pubmed/22154076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.10.006 |
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