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Unravelling mechanisms of p53-mediated tumour suppression

p53 is a crucial tumour suppressor that responds to diverse stress signals by orchestrating specific cellular responses, including transient cell cycle arrest, cellular senescence and apoptosis, which are all processes associated with tumour suppression. However, recent studies have challenged the r...

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Detalhes bibliográficos
Main Authors: Bieging, Kathryn T., Mello, Stephano Spano, Attardi, Laura D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049238/
https://ncbi.nlm.nih.gov/pubmed/24739573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3711
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