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Unravelling mechanisms of p53-mediated tumour suppression

p53 is a crucial tumour suppressor that responds to diverse stress signals by orchestrating specific cellular responses, including transient cell cycle arrest, cellular senescence and apoptosis, which are all processes associated with tumour suppression. However, recent studies have challenged the r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bieging, Kathryn T., Mello, Stephano Spano, Attardi, Laura D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049238/
https://ncbi.nlm.nih.gov/pubmed/24739573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3711
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