Llwytho...

Synthesis of 8-oxo-dGTP and its β,γ-CH(2)-, β, γ-CHF-, and β, γ-CF(2)- analogues

Three novel 8-oxo-dGTP bisphosphonate analogues of 3 in which the bridging β,γ-oxygen is replaced by a methylene, fluoromethylene or difluoromethylene group (4–6, respectively) have been synthesized from 8-oxo-dGMP 2 by reaction of its morpholine 5’-phosphoramidate 14 or preferably, its N-methylimid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Tetrahedron Lett
Prif Awduron: Zheng, Yiying, Haratipour, Pouya, Kashemirov, Boris A., McKenna, Charles E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951955/
https://ncbi.nlm.nih.gov/pubmed/33716328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2021.152890
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