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Kinetic Effects of β,γ-Modified Deoxynucleoside 5′-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA
A recently described DNA polymerase ribozyme, obtained by in vitro evolution, provides the opportunity to investigate mechanistic features of RNA catalysis using methods that previously had only been applied to DNA polymerase proteins. Insight can be gained into the transition state of the DNA polym...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024617/ https://ncbi.nlm.nih.gov/pubmed/33356161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00779 |
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