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Protection-free One-pot Synthesis of 2′-Deoxynucleoside 5′-Triphosphates and DNA Polymerization

[Image: see text] By differentiating the functional groups on nucleosides, we have designed and developed a one-pot synthesis of deoxyribonucleoside 5′-triphosphates without any protections on the nucleosides. A facile synthesis is achieved by generating an in situ phosphitylating reagent that react...

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Autors principals: Caton-Williams, Julianne, Smith, Matthew, Carrasco, Nicolas, Huang, Zhen
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163101/
https://ncbi.nlm.nih.gov/pubmed/21790120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201073e
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