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Synthesis and Characterization of the Oxidized dGTP Lesions Spiroiminodihydantoin-2′-deoxynucleoside-5′-triphosphate and Guanidinohydantoin-2′-deoxynucleoside-5′-triphosphate
Two convenient synthetic routes to the oxidized guanosine triphosphate lesions spiroiminodihydantoin-2′-deoxynucleoside-5′-triphosphate (dSpTP) and guanidinohydantoin-2′-deoxynucleoside-5′-triphosphate (dGhTP) are reported. Both two-electron oxidation of 2′-deoxy-7,8-dihydro-8-oxoguanosine-5′-tripho...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442819/ https://ncbi.nlm.nih.gov/pubmed/16497015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052484t |
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