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Synthesis and Characterization of the Oxidized dGTP Lesions Spiroiminodihydantoin-2′-deoxynucleoside-5′-triphosphate and Guanidinohydantoin-2′-deoxynucleoside-5′-triphosphate

Two convenient synthetic routes to the oxidized guanosine triphosphate lesions spiroiminodihydantoin-2′-deoxynucleoside-5′-triphosphate (dSpTP) and guanidinohydantoin-2′-deoxynucleoside-5′-triphosphate (dGhTP) are reported. Both two-electron oxidation of 2′-deoxy-7,8-dihydro-8-oxoguanosine-5′-tripho...

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Autors principals: Ye, Yu, Muller, James G., Burrows, Cynthia J.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442819/
https://ncbi.nlm.nih.gov/pubmed/16497015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052484t
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