Nalaganje...
Halogenated β,γ-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase β: structural evidence for stereospecific binding of the fluoromethylene analogues
β,γ-Fluoromethylene analogues of nucleotides are considered to be useful mimics of the natural substrates, but direct structural evidence defining their active site interactions has not been available, including the influence of the new chiral center introduced at the CHF carbon, as in β,γ-fluoromet...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891752/ https://ncbi.nlm.nih.gov/pubmed/20465217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909370k |
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