Rapamycin-Loaded Lipid Nanocapsules Induce Selective Inhibition of the mTORC1-Signaling Pathway in Glioblastoma Cells

Inhibition of the PI3K/Akt/mTOR signaling pathway represents a potential issue for the treatment of cancer, including glioblastoma. As such, rapamycin that inhibits the mechanistic target of rapamycin (mTOR), the downstream effector of this signaling pathway, is of great interest. However, clinical...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Séhédic, Delphine, Roncali, Loris, Djoudi, Amel, Buchtova, Nela, Avril, Sylvie, Chérel, Michel, Boury, Frank, Lacoeuille, Franck, Hindré, François, Garcion, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947795/
https://ncbi.nlm.nih.gov/pubmed/33718332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.602998
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