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mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease
Rapamycin slows disease progression in the male Han:SPRD (Cy/+) rat with polycystic kidney disease (PKD). The aim of this study was to determine the effect of rapamycin on PKD and the relative contributions of the proproliferative mammalian target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2) i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023230/ https://ncbi.nlm.nih.gov/pubmed/20943770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00129.2010 |
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