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Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD)

Background. Short-term studies have demonstrated that rapamycin or everolimus treatment decreases cyst formation and improves renal function in animal models of polycystic kidney disease (PKD). Autosomal dominant polycystic kidney disease (ADPKD) patients would likely require life-long treatment wit...

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Detalhes bibliográficos
Main Authors: Zafar, Iram, Belibi, Franck A., He, Zhibin, Edelstein, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727300/
https://ncbi.nlm.nih.gov/pubmed/19321761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp129
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