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Rapamycin and mTORC1 Inhibition in the Mouse: Skin Cancer Prevention

Therapeutic and preventive effects of rapamycin include reduced risk of non-melanoma skin cancer (NMSC). In this issue of the journal (beginning on page XXX), Checkley et al. report that rapamycin inhibits mammalian target of rapamycin (mTOR) complex 1 in murine epidermis, thereby inhibiting tumor p...

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Detalhes bibliográficos
Main Authors: Athar, Mohammad, Kopelovich, Levy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136877/
https://ncbi.nlm.nih.gov/pubmed/21733819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0266
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