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Natural Selection on the Phase-Separation Properties of FUS during 160 My of Mammalian Evolution

Protein phase separation can help explain the formation of many nonmembranous organelles. However, we know little about its ability to change in evolution. Here we studied the evolution of the mammalian RNA-binding protein Fused in Sarcoma (FUS), a protein whose prion-like domain (PLD) contributes t...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Dasmeh, Pouria, Wagner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947763/
https://ncbi.nlm.nih.gov/pubmed/33022038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa258
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