The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein Fused in Sarcoma (FUS) undergoes LLPS and mut...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://ncbi.nlm.nih.gov/pubmed/34233002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab582
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