The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein Fused in Sarcoma (FUS) undergoes LLPS and mut...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://ncbi.nlm.nih.gov/pubmed/34233002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab582
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