The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein Fused in Sarcoma (FUS) undergoes LLPS and mut...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
RNA and RNA-protein complexes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://ncbi.nlm.nih.gov/pubmed/34233002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab582
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