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Molecular interactions underlying liquid-liquid phase separation of the FUS low complexity domain
The low complexity domain of the RNA-binding protein FUS (FUS LC) mediates liquid-liquid phase separation (LLPS), but interactions between the repetitive SYGQ-rich sequence of FUS LC that stabilize the liquid phase are not known in detail. By combining NMR and Raman spectroscopy, mutagenesis, and mo...
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Publicado no: | Nat Struct Mol Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613800/ https://ncbi.nlm.nih.gov/pubmed/31270472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0250-x |
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