The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein Fused in Sarcoma (FUS) undergoes LLPS and mut...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
RNA and RNA-protein complexes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287939/
https://ncbi.nlm.nih.gov/pubmed/34233002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab582
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