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Natural Selection on the Phase-Separation Properties of FUS during 160 My of Mammalian Evolution

Protein phase separation can help explain the formation of many nonmembranous organelles. However, we know little about its ability to change in evolution. Here we studied the evolution of the mammalian RNA-binding protein Fused in Sarcoma (FUS), a protein whose prion-like domain (PLD) contributes t...

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Dasmeh, Pouria, Wagner, Andreas
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947763/
https://ncbi.nlm.nih.gov/pubmed/33022038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa258
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