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Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability
Protein abundance affects the evolution of protein genotypes, but we do not know how it affects the evolution of protein phenotypes. Here we investigate the role of protein abundance on the evolvability of green fluorescent protein (GFP) towards the novel phenotype of cyan fluorescence. We evolve GF...
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| Publicat a: | Nat Ecol Evol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2022
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613228/ https://ncbi.nlm.nih.gov/pubmed/35798838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-022-01797-w |
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