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Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability
Protein abundance affects the evolution of protein genotypes, but we do not know how it affects the evolution of protein phenotypes. Here we investigate the role of protein abundance on the evolvability of green fluorescent protein (GFP) towards the novel phenotype of cyan fluorescence. We evolve GF...
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| Publicado no: | Nat Ecol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613228/ https://ncbi.nlm.nih.gov/pubmed/35798838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-022-01797-w |
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